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Neurosurgery

Dear Friends NEUROSURGERY at the International Symposium on Pediatric Neuro-Oncology Convention Centre, Liverpool 12th – 15th June 2016

We take great pleasure in welcoming you to ISPNO and to Liverpool, a vibrant city with a rich maritime, art and musical heritage – one of the most visited cities in the United Kingdom. We promise you an amazing, not to be missed, conference that will be a landmark event in the science and clinical practice of Pediatric Neuro-Oncology. The conference venue is the award winning Liverpool Convention Centre set on a delightful waterfront that has achieved world heritage status. The meeting will follow the successful format of previous ISPNO meetings with a full program of plenary and poster sessions, keynote talks and round table discussions covering all the main aspects of Pediatric Neuro-Oncology. We will offer a memorable networking and social program with the Welcome Reception at the brilliantly designed waterside Museum of Liverpool, a fantastic gala dinner and optional social events at the Cavern Club – home of the Beatles – or a Latin themed evening at the fabulous Alma de Cuba restaurant. Give the importance of NEUROSURGERY in the management of children and young people with CNS tumours, for the first time, the ISPNO meeting has a whole day (Monday 13th June) dedicated to neurosurgical topics.  In addition we will host a pre-ISPNO workshop on Neuro-physiology intra-operative monitoring (please see ISPNO Website for details). For the Neurosurgical Day, we have created a vibrant program that features the leading international experts in Paediatric Neurosurgery. Sessions include those on:

  1. Intraoperative Neurophysiology During Brainstem and Spinal Cord Surgery in Children
  2. Debate: ‘Should neurophysiological monitoring be a standard of care in brainstem and spinal cord surgery?’
  3. Novel / Advanced Techniques for Brain Tumours (IOMRI, Brain mapping, advanced endoscopy).
  4. Debate: The role of advanced technology in brain tumours: do we really need it?
  5. Lunchtime session on ‘Drug Delivery techniques for Brain Tumours’.
  6. Imaging in Pediatric Neuro-Oncology.

The attendees at the Neurosurgery Day will then join the main ISPNO meeting for a stimulating session on Cerebellar Mutism. I am sure you will agree this is an exciting program and all those involved in Pediatric Neurosurgery will be highly stimulated and informed. There is facility to register just for the Neurosurgery day but there is of course much to be gained from the ISPNO as a whole and neurosurgical colleagues are encouraged to register for the whole meeting to take advantage of the rich scientific program and networking experience. Please register as soon as possible to talk advantage of our early bird registration rates.  Tickets for the gala dinner and optional events are limited, so don’t miss out! A full range of hotels can be booked all of which are within walking distance of the Convention Centre. We also look forward to receiving your abstracts for this global congress. We look forward to welcoming the international pediatric neurosurgery community to Liverpool. With Very Best Wishes Conor Mallucci Benedetta Pettorini Chris Parks Shivaram Avula Barry Pizer On behalf of the Local Organising Committee of ISPNO 2016 – Liverpool.

Speakers

Dr Frederick A Boop

Dr Frederick A BoopDr Frederick Boop obtained his Bachelor of Arts Degree from the University of Arkansas in 1978. He received his Medical Degree in 1983 from the University of Arkansas for Medical Sciences. He completed his Internship at the University of Texas Health Science Center in 1984, and also his Neurosurgical Residency, which he completed in 1989. In 1989 Dr Boop completed a Fellowship in Epilepsy and Functional Neurosurgery at the University of Minnesota, and in 1990 a Pediatric Neurosurgery Fellowship at Arkansas Children’s Hospital. He is certified by the American Board of Neurological Surgery and American Board of Pediatric Neurological Surgery. Dr Boop is currently Professor and James T. Robertson Chair, of Neurosurgery at the University of Tennessee, and a member of the Semmes-Murphey Neurologic and Spine Institute, and Chief of Pediatric Neurosurgery St. Jude Children’s Research Hospital. His special interests include Pediatric and adult neuro-oncology, epilepsy surgery, and craniosynostosis. Dr Boop is married to Lee Ann and they have two children. Dr Boop currently has grants to study the molecular genetic events causing brain tumors and to study the molecular genetics of epilepsy. He is also involved principle investigator in multi-center clinical trials of brain tumor treatments. American Medical Association, American Association of Neurological Surgeon, American Epilepsy Society, Congress of Neurological Surgeons, National Association of Epilepsy Centers, North American Skull Base Society, American College of Surgeons, New York Academy of Sciences, American Board of Neurological Surgery, Joint Council of State Neurosurgical Societies, Southern Neurosurgical Society, , Neurosurgical Society of America, Society of Neurological Surgeons, Fellow-American Academy of Pediatrics, Memphis and Shelby County Medical Society. Past President of the American Society of Pediatric Neurosurgery. Secretary American Society of Neurological Surgeons. Dr Boop is the President Elect of the American Association of Neurological Surgeons (AANS) and Chairman of the American Board of Paediatric Neurosurgery.

Professor Giuseppe Cinalli

Professor Giuseppe CinalliDr Giuseppe Cinalli is a Neapolitan by birth and currently the Head, Department of Pediatric Neurosurgery of the ‘Santobono-Pausilipon Children’s Hospital’ of home city and Assistant Professor in Pediatric Neurosurgery, L’Aquila University, Italy. Dr Cinalli is married and has two children. He undertook his medical studies and subsequently his residency in neurosurgery at the University “Federico II” of Naples. He was a fellow at the Department of Paediatric Neurosurgery, Hôpital Necker-Enfants Malades of Paris, France. He was a visiting Fellow at the Department of Pediatric Neurosurgery of the ‘New York University Medical Center’ directed by Prof. Fred Epstein and at the Department of Pediatric Neurosurgery of the University of Utah directed by Prof. Marion Walker. Dr Cinalli was a faculty member of the Department of Paediatric Neurosurgery, Hôpital Necker-Enfants Malades of Paris prior to returning to his native city. He is active in paediatric neurosurgery training in Italy and, in Europe through the European Society of Paediatric Neurosurgery (ESPN) and Internationally through Federation of International Neuroendoscopy (FINE). He is the secretary of the latter. He has co-edited seminal books: ‘Paediatric hydrocephalus’, ‘Spinal bifida – management and outcome’ and this year the ‘Paediatric Posterior fossa surgery’. He has over 80 peer-reviewed publications and has delivered over 100 lectures nationally and Internationally.

Professor Tony Figaji

Professor Tony FigajiTony Figaji is the Professor and Head of Paediatric Neurosurgery at the University of Cape Town and Red Cross War Memorial Children’s Hospital, South Africa. He is head of the Neurocritical Care and the Intraoperative Neurophysiology programs, for which he runs a fellowship program in each. He holds the National Research Foundation SARChI Chair of Clinical Neurosciences and is on the executive boards of the Intraoperative Neurophysiology Society and the International Neurotrauma Society, the latter of which he serves as current vice president. Apart from general paediatric neurosurgery, he is particularly interested in neuro-oncology surgery. His research interests broadly centre on acute brain pathophysiology and he currently runs projects on biomarkers in traumatic brain injury and meningitis, mediators of brain inflammation, microdialysis-based brain chemistry and cerebral drug recovery, and molecular biology of brain tumours.

Zoltan Patay MD, PhD

Zoltan PatayChief of Neuroimaging, St. Jude Children’s Research Hospital, Memphis, TN, USA Zoltan Patay is a board certified neurologist and radiologist with subspecialty qualification in neuroradiology and special expertise in pediatric neuroradiology. He trained in Hungary, France and Belgium and worked for 10 years in the King Faisal Specialist Hospital and Research Center in Riyadh, Saudi Arabia before moving to the USA. Over his 34 years of professional career his main areas of interest have been the non-invasive, MRI-based evaluation of cerebrovascular diseases (MR neuroangiography), neurometabolic disorders (in particular the comprehensive MRI evaluation of CNS involvement) and multimodality quantitative parametric imaging in pediatric neuro-oncology. Currently, he focuses on a.) The phenomenon of diaschisis in the central nervous system and its clinical implications (postoperative posterior fossa syndrome, in particular, b.) Conventional as well as quantitative MR-based analysis of diffuse intrinsic pontine gliomas, and c.) Imaging genomics in embryonal tumors of the central nervous system (including medulloblastoma and ATRT).

Professor Charlie Teo

Dr Frederick A BoopProfessor Charlie Teo is a US Board Certified paediatric neurosurgeon who is the Director of the Centre for Minimally Invasive Neurosurgery in Sydney, Australia, the Yeoh Ghim Seng Visiting Professor of Neurosurgery at the National University Hospital, Singapore, and Consulting Professor at Duke University Medical College in the USA. During his time in the USA, he was the Founder and Director of the Arkansas Pediatric Neuro-oncology Clinic and Chief of Neurosurgery at the Arkansas Children’s Hospital. He is the Founder of the Cure Brain Cancer Foundation which has raised over $12 million in the last 3 years alone for brain cancer research both in Australia and worldwide. The author of “Principles and Practice of Keyhole Brain Surgery” he has been a tireless advocate for minimising collateral damage while maximising tumour resection. He has one of the world’s largest surgical series of brainstem gliomas.

Jeffrey H. Wisoff

Professor Tony FigajiJeffrey H. Wisoff, M.D., is the Director of the Division of Pediatric Neurosurgery at the New York University Langone Medical Center and Professor of Neurosurgery and Pediatrics at the New York University School of Medicine. He graduated summa cum laude and Phi Beta Kappa from Union College and received his medical degree, with honors, from George Washington University School of Medicine. Dr. Wisoff completed his Neurosurgery residency at NYU under Joseph Ransohoff, M.D., followed by a fellowship in Pediatric Neurosurgery under Fred Epstein, M.D.. Dr. Wisoff was a founding member of the NYU Division of Pediatric Neurosurgery in 1985 and assumed its Directorship in 1996. During the past 30 years he has made major innovative contributions to the surgical treatment of neurological disorders in children, and congenital problems in adults, in particular to the treatment of brain tumors, Chiari malformations, hydrocephalus and craniosynostosis. He has published over 250 scientific articles, abstracts, and book chapters. Dr.Wisoff is the past Co-Chairman of the Neurosurgery Committee and a senior member of the Brain Tumor Strategy Committee of the national Children’s Oncology Group. He is the chair of the COG 9891 Low-grade Astrocytoma Protocol, a prospective, international study of the surgical treatment of over 700 children with low-grade pediatric brain tumors. Dr. Wisoff is the past Chairman of the Joint Section of Pediatric Neurosurgery of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, and is a member of the American Society of Pediatric Neurosurgery and the International Society for Pediatric Neurosurgery. He also serves on the medical advisory board of the Children’s Brain Tumor Foundation, the Israel Pediatric Brain Tumor Foundation, the Posterior Fossa Society, and the Hydrocephalus Association. Dr. Wisoff is on the editorial board of the Polish Journal of Neurology and Neurosurgery and has been a reviewer for Journal of Neurosurgery, Journal of Neurosurgery: Pediatrics, Neurosurgery, Pediatrics, and Journal of Neuro-Oncology. He has served as an ad hoc reviewer for the National Institutes of Health and National Cancer Institute Study Sections. Among his many honors, Dr Wisoff has been an invited speaker and visiting professor at Stanford University, Harvard’s Brigham and Children’s Hospital, Mt Sinai, Weill Cornell Medical Center, University of Georgia and numerous international sites, including Israel, Poland, Brazil, Argentina and Japan. He has been recognized by Castle Connelly in their publications as one of the Top Doctors in the New York Metro area since 1997, America’s Top Doctors since 2000, and America’s Top Doctors in Cancer since its inception in 2005 . He has consistently been recognized in New York Magazines annual review of physicians. He has received NYU Medical Center’s KiDS of NYU Physician, and the Children’s Brain Tumor Foundation Physician Award, twice the Rifkah Laufer Bikur Cholim Rofeh Award.

 Stephanie PugetStephanie Puget Stephanie Puget is currently senior pediatric neurosurgeon in the department of Pediatric Neurosurgery in Necker Enfants Malades Hospital, Professor of neurosurgery at Paris Cité Sorbonne, Paris Descartes University in Paris and Head of the Oncology Program in the same department. Apart from general paediatric neurosurgery, her fields of particular interests are (1) Neuro-oncology in clinical as well as fundamental research. She was awarded for her research on the molecular biology of ependymomas (ASCO Bridgit leventhal Merit Award, 2007). Her present work is mainly on craniopharyngiomas, DIPG and cerebellar mutism. (2) Research and development of strategies on the improvement of the children’s quality of life with prospective studies in arachnoid cysts and craniopharyngiomas (Chairman of the Craniopharyngioma SIOPe comity). She has published over 100 peer-reviewed publications and book chapters. She was invited in many international congresses and courses.

Pic_Conor MallucciConor Mallucci, MB BS, FRCS (Surgical Neurology) Having qualified in London at University College in 1989 he went on to train in neurosurgery in Birmingham, Nottingham and then Paris. Conor is committed to the development of his field and in improving outcomes in children with brain tumours and hydrocephalus. He is chairman of the British Paediatric Neurosurgery research group and currently Chief Investigator for the BASICS trial, a NIHR funded multicentre National randomised trial on shunt infection. Having published extensively in the literature on brain tumours, hydrocephalus and technical advances in neurosurgery such as Intra-operative MRI, he now has over 115 publications in international peer reviewed journals and has edited and published an International collaborative textbook on CSF disorders. He is currently deputy editor of the British Journal of Neurosurgery and an associate editor of the journal Child’s Nervous System. He sits on the executive boards of both the European and International Societies of Paediatric Neurosurgery and is exiting co –chairman of the SIOP-E craniopharyngioma group. He is the the National surgical representative for the Ependymoma SIOP II study about to open in the UK and also for the SIOP germ cell II study. He is Clinical Director of the North West NHS paediatric neuroscience operational delivery network. He remains clinical lead for the department of paediatric neurosurgery at Alder Hey, Liverpool and is clinical lead for Neuro-oncology.